Print Overview Mesentery Enlarge image Close Mesentery Mesentery The mesentery is a fold of membrane that attaches the intestine to the wall around the stomach area and holds it in place. Mesenteric lymphadenitis is swelling of the lymph nodes in the mesentery. Lymphadenitis is a condition in which the small round or bean-shaped clusters of cells, called lymph nodes, become swollen and inflamed. The swelling can affect the lymph nodes in the membrane that connects the bowel to the wall around the stomach area, called the mesentery. Then the condition is called mesenteric lymphadenitis (mez-un-TER-ik lim-fad-uh-NIE-tis). An infection in the intestines, such as a virus, is the usual cause of mesenteric lymphadenitis. Also called mesenteric adenitis, the condition mainly affects children and teens. Mesenteric lymphadenitis can act like appendicitis or a condition in which part of the intestine slides into another part of the intestine, called intussusception. Unlike appendicitis or intussusception, mesenteric lymphadenitis usually clears up on its own.Products & ServicesA Book: Mayo Clinic Family Health Book, 5th EditionNewsletter: Mayo Clinic Health Letter — Digital EditionShow more products from Mayo Clinic SymptomsPossible symptoms of mesenteric lymphadenitis include: Pain in the stomach area, often on the lower right side, but the pain can be more spread out. General tenderness of the stomach area. Fever. Enlarged mesenteric lymph nodes. Depending on what's causing the condition, symptoms also might include: Diarrhea. Nausea and vomiting. When to see a doctorPain in the stomach area is common in children and teens. So it can be hard to know when to seek medical advice. Call a health care provider right away for a child who has: Sudden, severe pain in the stomach area. Stomach area pain with fever. Stomach area pain with diarrhea or vomiting. Tenderness to touch of the stomach area. Bloody or maroon-colored stool. Also, call a health care provider for a child who has pain in the stomach area that doesn't get better in a short time and who also: Has a change in bowel habits. Has a loss of appetite. Is not able to sleep. CausesThe most common cause of mesenteric lymphadenitis is a viral infection, such as gastroenteritis. Gastroenteritis is often called stomach flu. This infection causes swelling in the lymph nodes in the thin tissue that attaches the intestine to the back of the wall around the stomach area, called mesentery. Other causes of mesenteric lymphadenitis include bacterial infection, inflammatory bowel disease and lymphoma. By Mayo Clinic Staff Request an appointment Diagnosis & treatment Sept. 09, 2023 Print Show references Nauman MI. Causes of acute abdominal pain in children and adolescents. https://www.uptodate.com/contents/search. Accessed March 8, 2023. Ferri FF. Mesenteric adenitis. In: Ferri's Clinical Advisor 2023. Elsevier; 2023. https://www.clinicalkey.com. Accessed March 8, 2023. Mesenteric adenitis. Radiopaedia.org. https://radiopaedia.org/articles/mesenteric-adenitis?lang=us. Accessed March 8, 2023. Ozdamar MY, et al. Acute mesenteric lymphadenitis in children: Findings related to differential diagnosis and hospitalization. Archives of Medical Science. 2020; doi:10.5114/aoms.2018.79430. AAP Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2022-2023. Pediatrics. 2022; doi:10.1542/peds.2022-059274. Sullivan JE, et al. Fever and antipyretic use in children. Pediatrics. 2011; doi:10.1542/peds.2010-3852. Reaffirmed October 2022. Labeling of drug preparations containing salicylates. Electronic Code of Federal Regulations. https://www.ecfr.gov/current/title-21/chapter-I/subchapter-C/part-201/subpart-G/section-201.314. Accessed Jan. 26, 2023. Fine AL (expert opinion). Mayo Clinic. Jan. 25, 2023. Hoecker JL (expert opinion). Mayo Clinic. March 9, 2023. Related Associated Procedures Abdominal ultrasound Products & Services A Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Mesenteric lymphadenitisSymptoms&causesDiagnosis&treatment Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Mayo Clinic on Incontinence - Mayo Clinic PressMayo Clinic on IncontinenceThe Essential Diabetes Book - Mayo Clinic PressThe Essential Diabetes BookMayo Clinic on Hearing and Balance - Mayo Clinic PressMayo Clinic on Hearing and BalanceFREE Mayo Clinic Diet Assessment - Mayo Clinic PressFREE Mayo Clinic Diet AssessmentMayo Clinic Health Letter - FREE book - Mayo Clinic PressMayo Clinic Health Letter - FREE book CON-20193989 Patient Care & Health Information Diseases & Conditions Mesenteric lymphadenitis